Check out the warning below that Smarthome includes in their literature for the 2414U Insteon controller:
Using PowerLinc USB & PowerLinc Controller with DirectX Input Devices
It is advised that you unplug your PowerLinc when playing games that use Microsoft\’s DirectX system while using USB input devices like joysticks.
I have run into this problem in the past… Â It doesn\’t cause harm to your automation controller (2414U or 1132U), but if you have either plugged in and you start a game that uses a DirectX Â input device, it\’s possible that the application/game will crash… Â Or become stuck at a black screen.
Simply unplugged the controller or the cable to the controller will allow the application/game to run successfully.
Evidently there is a conflict  between DirectX and the controller\’s driver…